Read that deeply and you stop guessing at which bacteria are there, and start knowing what each one can do. That is the difference between a formula for you and a formula for someone roughly like you.
Method governed by a seven-person science board.Meet them →
We are not a probiotic. We are one of one.
Easier to say what we are not. Three things this is regularly mistaken for, and why none of them is it.
Not a probiotic.
One blend of bacteria, made the same for everyone, decided long before anyone looked at a single gut. Convenient for whoever is making it. Ours is chosen strain by strain from your sample.
Not a synbiotic.
A synbiotic pairs bacteria with fibre, which is right in principle and generic in practice. We pair each strain with the fibre it feeds on, at the dose your gut ferments.
Not a stack.
A stack is what you build yourself out of labels, forum threads and hope. This is one formula, built from a reading, signed off by a scientist before it is made.
What it is.
One formula, built from your own reading. Live cultures, the fibres that feed them, and the vitamins and minerals your levels call for — nothing in it your biology did not ask for.
How we read you
We start by reading you — two ways on Core, three on Advanced. We never start with a formula and look for who it fits.
Dr. Polina Novikova
Chief Scientific Officer · PhD Bioinformatics
Your gut
The deep read
We find out exactly which bacteria are in your gut, and what each one can do. Everything in your formula starts here.
Every plan
Your intake
What you want to work on, what you already take, and anything a doctor should know. So your formula fits your life.
Every plan
Your blood
A blood test shows which of your levels sit lower than average, and your formula is built around that. Measured again next cycle.
Advanced
Your formula
Nothing goes into your formula without a reason.
Most gut tests read who's there. We read what they can do.
The same gut. The same microbes, read two completely different ways.
Almost every gut test
Who's there
16S rRNA
Every microbe is just a dot. All you learn is that it exists.
Our method
What each one can do
Shotgun sequencing
Tap a glowing microbe to see its job
01Which species it is
02What it can ferment
03What it produces
04Whether it is thriving
Active
Low
Missing
16S tells you, per microbe
A list of names. No idea what any of them do.
We tell you, per microbe
Every name, the job behind it, and the jobs nobody can do.
Every organism in your sample, read in full.
Ten minutes of your time buys three weeks of ours. Sequencing, reading, building, sign-off. None of it can start before your sample arrives, which is the whole point.
Organisms read from one sample
1,217
Resolution
Species & strain
Sequenced in
EU laboratories
Turnaround from receipt
Two weeks
Made before your reading
Nothing
A supplement that could ship tomorrow was made before anyone looked at you.
Four hundred Latin names, and the rest is your problem.
That is what most microbiome tests deliver for around €150. A list, a percentage beside each name, and a cheerful note about eating more fibre. It looks like science. It is an inventory.
What €150 usually buys
Bacteroides uniformis8.4%
Faecalibacterium prausnitzii6.1%
Prevotella copri5.7%
Eubacterium rectale4.9%
Bacteroides vulgatus4.3%
Roseburia intestinalis3.8%
+ 390 more species
Impressive to look at. Impossible to act on. And that is the entire deliverable.
An inventory is not an analysis.
Knowing you carry 4.3% Bacteroides vulgatus is trivia until someone works out what it is doing, who it is doing it with, and whether that is a problem. Most of the category stops before that, because a list is cheap to produce and looks like proof. We read it three ways instead.
01
Sorted into teams
Not by name. By the job each species actually performs, then checked against the range that job should sit in.
02
Weighed as ratios
Because a team can be the right size and still be losing. Four ratios show whether the cascade is doing its job.
03
Settled into one score
Five pillars, one number, and the name of your weakest pillar. That is the one your formula is built to move.
Every gut is unique. The patterns behind them are not.
Across more than 8,000 studied guts, the same symptoms keep tracing back to the same eight mechanisms. Each one needs a different formula.
What is actually going on
Protein fermentation running hot
The protein-fermenting team has grown past its range. That tips the gut toward protein for fuel, which usually shows up as more gas and a less favourable mix of by-products.
What is actually going on
Low bifido backbone
Bifidobacteria are scarce, so the acetate base the rest of the ecosystem feeds on is thin. It is the most common pattern we see, in roughly 44% of samples.
What is actually going on
Weak fibre fermentation
Fibre goes in but little comes of it. The fibre-to-butyrate chain is underfed, so there is little capacity left to turn it into butyrate.
What is actually going on
Mucus barrier wearing thin
Mucus-layer bacteria have overgrown while the butyrate team runs thin, so the gut mucus layer tends to get used as fuel and left under-supported at the same time.
What is actually going on
Fibre processors crowded out
One mucus-feeding strain, Akkermansia, has overgrown and crowded out the fibre-handling teams, so the butyrate chain falls away and the gut leans on its own lining for fuel.
What is actually going on
Broad depletion
Several teams are low at once, often after antibiotics or illness. The whole chain needs rebuilding, not a single fix.
What is actually going on
Gut-brain stress signals
The microbiome itself can read well here. This pattern comes from your questionnaire, not your composition: stress and sleep are pulling on the gut through the gut-brain axis.
What is actually going on
In balance, holding steady
All six teams sit within range and the ecosystem is carbohydrate-driven. No acute imbalance to correct.
The 200–400 species in your sample, sorted into six teams by the job they do and checked against each team’s healthy range.
Team sizes show who is there. These four show whether the fermentation cascade is actually working.
Fibre · break down fibreIn range
This reading30%
80%
Healthy 30–50%
Butyrate · make butyrateIn range
This reading16%
40%
Healthy 10–25%
Cross-feeders · pass nutrients alongIn range
This reading9%
19%
Healthy 6–12%
Bifido · feed the acetate baseIn range
This reading3%
16%
Healthy 2–10%
Mucus · turn over the mucus layerIn range
This reading3%
6%
Healthy 1–4%
Protein · ferment proteinOver range
This reading11%
13%
Healthy 1–5%
Main fuel preference
Protein-drivenCarbohydrate-driven
Fermentation efficiency
StalledEfficient
Gut-lining dependence
Feeding on the liningDiet-fed
Harsh by-products
PutrefactiveSCFA-dominant
Where the formula would focus: Crowd the protein-fermenters back out with competitive and antimicrobial strains, and tip fermentation back toward fibre.
Fibre · break down fibreIn range
This reading35%
80%
Healthy 30–50%
Butyrate · make butyrateIn range
This reading18%
40%
Healthy 10–25%
Cross-feeders · pass nutrients alongIn range
This reading9%
19%
Healthy 6–12%
Bifido · feed the acetate baseUnder range
This reading0.4%
16%
Healthy 2–10%
Mucus · turn over the mucus layerIn range
This reading2.5%
6%
Healthy 1–4%
Protein · ferment proteinIn range
This reading3%
8%
Healthy 1–5%
Main fuel preference
Protein-drivenCarbohydrate-driven
Fermentation efficiency
StalledEfficient
Gut-lining dependence
Feeding on the liningDiet-fed
Harsh by-products
PutrefactiveSCFA-dominant
Where the formula would focus: Rebuild the bifidobacteria with selective strains and fibres (GOS, inulin), so the rest of the chain has something to cross-feed on.
Fibre · break down fibreUnder range
This reading24%
80%
Healthy 30–50%
Butyrate · make butyrateUnder range
This reading8%
40%
Healthy 10–25%
Cross-feeders · pass nutrients alongIn range
This reading8%
19%
Healthy 6–12%
Bifido · feed the acetate baseIn range
This reading4%
16%
Healthy 2–10%
Mucus · turn over the mucus layerIn range
This reading3%
6%
Healthy 1–4%
Protein · ferment proteinIn range
This reading4%
8%
Healthy 1–5%
Main fuel preference
Protein-drivenCarbohydrate-driven
Fermentation efficiency
StalledEfficient
Gut-lining dependence
Feeding on the liningDiet-fed
Harsh by-products
PutrefactiveSCFA-dominant
Where the formula would focus: Restore the fibre-fermenting teams and the short-chain fatty acids they produce, with an oat beta-glucan-led blend.
Fibre · break down fibreUnder range
This reading29%
80%
Healthy 30–50%
Butyrate · make butyrateUnder range
This reading7%
40%
Healthy 10–25%
Cross-feeders · pass nutrients alongIn range
This reading8%
19%
Healthy 6–12%
Bifido · feed the acetate baseIn range
This reading4%
16%
Healthy 2–10%
Mucus · turn over the mucus layerOver range
This reading8%
9%
Healthy 1–4%
Protein · ferment proteinIn range
This reading4%
8%
Healthy 1–5%
Main fuel preference
Protein-drivenCarbohydrate-driven
Fermentation efficiency
StalledEfficient
Gut-lining dependence
Feeding on the liningDiet-fed
Harsh by-products
PutrefactiveSCFA-dominant
Where the formula would focus: Support the mucus layer and rebuild butyrate, easing the load on the mucus layer.
Fibre · break down fibreUnder range
This reading24%
80%
Healthy 30–50%
Butyrate · make butyrateUnder range
This reading8%
40%
Healthy 10–25%
Cross-feeders · pass nutrients alongIn range
This reading9%
19%
Healthy 6–12%
Bifido · feed the acetate baseIn range
This reading3%
16%
Healthy 2–10%
Mucus · turn over the mucus layerOver range
This reading12%
14%
Healthy 1–4%
Protein · ferment proteinIn range
This reading5%
8%
Healthy 1–5%
Main fuel preference
Protein-drivenCarbohydrate-driven
Fermentation efficiency
StalledEfficient
Gut-lining dependence
Feeding on the liningDiet-fed
Harsh by-products
PutrefactiveSCFA-dominant
Where the formula would focus: Give the fibre-handling teams room to expand and crowd the overgrown strain back out, with a high-load fibre blend.
Fibre · break down fibreUnder range
This reading18%
80%
Healthy 30–50%
Butyrate · make butyrateUnder range
This reading6%
40%
Healthy 10–25%
Cross-feeders · pass nutrients alongUnder range
This reading4%
19%
Healthy 6–12%
Bifido · feed the acetate baseUnder range
This reading0.5%
16%
Healthy 2–10%
Mucus · turn over the mucus layerIn range
This reading3%
6%
Healthy 1–4%
Protein · ferment proteinIn range
This reading4%
8%
Healthy 1–5%
Main fuel preference
Protein-drivenCarbohydrate-driven
Fermentation efficiency
StalledEfficient
Gut-lining dependence
Feeding on the liningDiet-fed
Harsh by-products
PutrefactiveSCFA-dominant
Where the formula would focus: Re-seed the depleted teams together, rebuilding the whole chain rather than chasing one team at a time.
Fibre · break down fibreIn range
This reading34%
80%
Healthy 30–50%
Butyrate · make butyrateIn range
This reading16%
40%
Healthy 10–25%
Cross-feeders · pass nutrients alongIn range
This reading9%
19%
Healthy 6–12%
Bifido · feed the acetate baseIn range
This reading4%
16%
Healthy 2–10%
Mucus · turn over the mucus layerIn range
This reading2.5%
6%
Healthy 1–4%
Protein · ferment proteinIn range
This reading3.5%
8%
Healthy 1–5%
Main fuel preference
Protein-drivenCarbohydrate-driven
Fermentation efficiency
StalledEfficient
Gut-lining dependence
Feeding on the liningDiet-fed
Harsh by-products
PutrefactiveSCFA-dominant
Where the formula would focus: Bring in the Lpc-37 live-culture strain alongside whatever ecological work the reading needs.
Fibre · break down fibreIn range
This reading38%
80%
Healthy 30–50%
Butyrate · make butyrateIn range
This reading18%
40%
Healthy 10–25%
Cross-feeders · pass nutrients alongIn range
This reading9%
19%
Healthy 6–12%
Bifido · feed the acetate baseIn range
This reading5%
16%
Healthy 2–10%
Mucus · turn over the mucus layerIn range
This reading2.5%
6%
Healthy 1–4%
Protein · ferment proteinIn range
This reading3%
8%
Healthy 1–5%
Main fuel preference
Protein-drivenCarbohydrate-driven
Fermentation efficiency
StalledEfficient
Gut-lining dependence
Feeding on the liningDiet-fed
Harsh by-products
PutrefactiveSCFA-dominant
Where the formula would focus: Protect a good ecosystem and keep it steady, rather than forcing change it does not need.
9:00▪▪▪ ⌃ ▮
◔
Your balance score
58
out of 100
Needs work
Health68
Diversity82
Metabolic64
Team balance62
Safety88
Lowest pillar: team balance. That is what the formula is built to move.
Your balance score
64
out of 100
Needs work
Health72
Diversity78
Metabolic82
Team balance72
Safety100
Lowest pillar: health. That is what the formula is built to move.
Your balance score
60
out of 100
Needs work
Health70
Diversity75
Metabolic68
Team balance66
Safety100
Lowest pillar: team balance. That is what the formula is built to move.
Your balance score
55
out of 100
Needs work
Health62
Diversity72
Metabolic70
Team balance58
Safety95
Lowest pillar: team balance. That is what the formula is built to move.
Your balance score
50
out of 100
Needs work
Health60
Diversity68
Metabolic62
Team balance52
Safety92
Lowest pillar: team balance. That is what the formula is built to move.
Your balance score
36
out of 100
Needs work
Health62
Diversity52
Metabolic60
Team balance48
Safety100
Lowest pillar: team balance. That is what the formula is built to move.
Your balance score
84
out of 100
Excellent
Health84
Diversity88
Metabolic86
Team balance88
Safety100
The score reads well. The work here is a targeted strain set, not an ecological rebuild.
Your balance score
88
out of 100
Excellent
Health86
Diversity92
Metabolic90
Team balance92
Safety100
The job here is to hold this, not disturb it.
Your reading in your nb1 account
8,069
gut metagenomes your reading is benchmarked against: a large, curated reference set.
reference metagenomes
26
countries represented in that set, so a healthy baseline is not drawn from one population.
countries in that set
155
signature species tracked against peer-reviewed references, in every reading.
signature species tracked
We build it
A formula built around what your gut can actually use.
Once we can see what your gut can do, we build one formula for it and nothing else. No two formulas come out the same, because no two readings are. Here is what goes into one, and how every choice gets made.
01First, the basics
The live cultures and prebiotic in your formula, dosed to work as one and decided by your reading.
Live cultures
Living bacteria you add to the gut, to top up the teams that are running short.
Prebiotics
The fibre those bacteria feed on. Their food source, nothing more complicated.
Combined
Both together: the exact fibre these strains can use, in the right amount, so they work as one system.
02The cultures, up close
Every strain we use, by name.
We do not add generic bacteria. We use strains: specific, named, trademarked versions of a bacterium, each with its own published research. A label that reads “probiotic blend” is naming none of this. Here is every one we work with.
The full library
All 19 strains
Bifidobacterium
animalis lactis
B420 · BB-12 · HN019
longum
BI-05 · 04 · 1714
breve
BR03 · B632
Lactobacillus
rhamnosus
GG
acidophilus
NCFM · LA-5
paracasei
Lpc-37 · UALpc-04
plantarum
299v · UALp-05 · Lpla33
reuteri
UALre-16
casei
431
Streptococcus
thermophilus
UASt-09
One formula draws on a handful of these, chosen by your reading, never by what we have in stock.
03Precision prebiotics
A strain we add is only worth adding if we feed it.
Every strain arrives paired with the exact fibre it feeds on. Which fibres, and how much of each, follows how your gut ferments — the same fibre behaves differently in every gut. Generic fibre is a guess. This is matched and measured.
The full library
All 13 fibres
Inulin
Galacto-oligosaccharides
GOS
Chicory Root Fibre
FOS
Oat Beta-Glucan
Partially Hydrolysed Guar Gum
PHGG
Resistant Starch
Hi-Maize
Psyllium Husk
Konjac Glucomannan
Acacia Fibre
Apple Pectin
Carob Bean Extract
soluble
Chitosan
Xanthan Gum
Your dose window
Too littleRight for youToo much
GOS
Inulin
PHGG
Beta-glucans
A few fibres, chosen from dozens. Only the ones your strains can actually use, each paired to the strain it feeds and dosed to the range you handle. Too little does nothing, too much brings the bloat. Two people never get the same blend.
04Everything on top
Made for one. Everything else is everyone else's.
The cultures and their fibres are the base. On top comes the rest of a 98-ingredient library, and only the parts your life asks for.
Chosen from 66
The supplement layer
Twenty-one vitamins and minerals, forty-five botanicals and compounds, every one of them vetted by our science board before it enters the library. Your formula draws only the ones your goals, lifestyle and diet call for.
21
Vitamins & minerals
45
Botanicals & compounds
A few of them
Omega-3 + D3
B-complex
Magnesium
Zinc
Ashwagandha
Curcumin
and more
What decides it
Your goals
What you have said you want to work on, in your own words.
Your intake form
What you already take, your diet and lifestyle, and anything a doctor should know.
What we screen for
The shortfalls common enough to check regardless of what you asked for.
Advanced only A blood panel then tunes these doses to levels we can measure, rather than to symptoms. What Advanced adds →
Every item traces back to something we read or something you told us. Nothing is in there by default.
Core reads you once. Advanced keeps reading.
Everything above is in every plan. Advanced adds three things, and they work as one loop: we measure again, we rebuild from the new numbers, and we add a blood panel so the doses land on measured levels rather than on how you say you feel.
Advanced only
Every cycle
The retest
We re-read your gut and your blood on the same methods, so the new numbers are comparable to the old ones rather than a fresh opinion.
The same eight patterns, re-scored
Your blood markers, measured again
Your overall score, measured again
You see what moved, and by how much
Every cycle
A rebuilt formula
Your formula is not topped up from the last one. It is built again from the new reading, so strains and doses follow where your gut has actually got to.
Strains that did their job are stepped down
Levels that read low pull in what they need
Fibres re-matched to how you now ferment
From cycle one
The blood panel
Your gut read says what your microbes can do. A blood panel says what actually reached you, so doses land on measured levels instead of on symptoms.
Vitamin D3, the most common shortfall
Homocysteine, for B-vitamin need
Omega-3 index and ferritin
You can start on Core and move up at any cycle boundary. Your existing reading carries over, so nothing is re-collected and nothing restarts.
The minds behind your formula.
The science here is young, and reading a gut this deeply sits at its edge. So we built a board to govern it: researchers who design the method, run it, and check it from outside, and hold every formula to what the evidence backs, not what a label would like to claim.
7
Specialists
3
Universities
290+
Publications
17,000+
Citations
The team that builds it
One pipeline, the same hands every time: the people who read your sample, work out what it means, and hold the build to clinical standards.
Chief Scientific Officer
Dr. Polina Novikova
PhD Bioinformatics, University of Luxembourg. Designs and runs the nb1 science pipeline end to end.
“The hard part of this work is leaving things out. If your reading doesn’t call for an ingredient, it isn’t in your formula, however good it looks on a label.”
PhD BioinformaticsUni. of Luxembourg
Bioinformatics
Dr. Monica S. Matchado
Microbiome functional profiling, TU Munich
“Anyone can list the bacteria in a sample. The real work is reading what that community is set up to do, because that’s what we build from.”
Immunology & gut health
Dr. Marijn Lewis
PhD Biomedical Sciences, University of Zurich
“An average is comfortable and almost always wrong for the person in front of you. Reading one gut properly is the only way to act on it.”
Clinical research
Katia B. Otterstedt
Clinical research & genomics, ECLIN
“A result you can’t reproduce isn’t a result. Every step from sample to formula has to hold up to the same checks, twice.”
Bioinformatics
Dr. Irina Utkina
Gut Microbiome Science · University of Toronto
“Personalised nutrition starts with understanding the microbiome beyond which microbes are present: what they are doing, how they affect health, and what we can change.”
Independently checked
Two of Europe’s most senior microbiome scientists review and challenge the method, with no stake in nb1.
Their job is to find where the science reaches further than the evidence allows, and to say so, before any of it reaches your formula.
Independent validator
Prof. Dr. Dirk Haller
Nutrition & Immunology · ZIEL Institute Director, TU Munich
“My role is to look for where the science is stretched too far. I keep agreeing to stay because, so far, it holds.”
TU MunichZIEL DirectorUEG Prize
Independent validator
Dr. Koen Venema
Gut Microbiology · Wageningen University
“Plenty of products call themselves personalised. Building from a real reading of the ecosystem is a different thing entirely, and it shows in the formula.”
254 publications17,000+ citations
So we start by reading yours.
Your kit ships first; your formula is produced after your analysis, never before.
Core
We read your gut, and build your formula from it.
£94/mo
Prefer no commitment? £99/mo, month-to-month, cancel anytime.