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Your first cycle, week by week

Give it sixteen weeks. Here's what changes.

Every supplement you've tried promised results "soon" and never said when. This one comes with a timeline built from your own gut reading, mapped across your first full cycle, and a reading at the end to show what actually moved. Here's what the weeks really look like.

Dr. Polina NovikovaProf. Dr. Dirk Hallernb1 science board

Built from your reading, measured against it every cycle. A timeline, not a promise.

Loved by early-access members through their first full cycle

The first cycle at a glance

  1. Day 0 Read your gut at home
  2. Weeks 1–4 Your formula begins
  3. Weeks 9–12 The change most members notice
  4. Week 16 We read you again & recalibrate

Your second month's on us on a 4 or 12-month plan. We'll email you how to claim it.

4 and 12-month plans only. The code cannot be used on the 1-month rolling plan.

You're in. Use code NB1FIRST at checkout on a 4 or 12-month plan to claim your second month, on us.
Meanwhile, see the full timeline

Why nothing's worked yet

It wasn't you. You were never given a timeline.

Every supplement you've tried worked the same way: take it, hope, wait for a payoff nobody ever defined, and quit when nothing obvious happened. With no timeline and nothing to measure, you were set up to give up.

  1. 1

    Start another supplement

    A probiotic, a fibre, whatever the reviews rated. No real idea what it's doing, or when it's meant to work.

  2. 2

    Wait, and wonder

    A week? A month? Nobody said. So you watch for a change with nothing to measure it against.

  3. 3

    Feel nothing you can point to

    Maybe a little better, maybe not. With no marker, you can't tell a real shift from a good day.

  4. 4

    Quietly give up

    You stop before anything could have landed. Back to square one, still guessing.

and on to the next bottle

A protocol should tell you when. And prove it when the time comes.

What to expect and when

Sixteen weeks, because biology takes sixteen weeks to shift.

Not a contractual lock. The minimum window in which real biological change can be measured, tracked month by month.

  1. Month 1

    Settling in

    Probiotic strains begin colonising. You may notice small shifts in digestion, normal as your gut adjusts.

  2. Month 2

    Early momentum

    SCFA production rebuilds as fibre supply stabilises. Energy and sleep often respond first.

  3. Month 3

    Deepening balance

    Team composition shifts measurably. Skin and immune markers tend to follow.

  4. Month 4

    The retest Advanced

    On Advanced, the same pipeline runs again, now with your first blood biomarker panel layered in alongside it. Your formula recalibrates against everything that shifted, in your gut and your blood. On Core, add a retest whenever you want to see your change.

What members report

Sleep, self-reported
▲ 2.0
Bloating, self-reported
▼ 5.0
Fatigue, self-reported
▼ 3.0
Stress, self-reported
▼ 2.0

We don't promise change. We show it to you.

Retest your gut and see exactly what moved. The same markers, re-measured before and after. One number, objectively re-scored.

80.2
/100
▲ 11.9 pts up from 68.3 Overall microbiome score

Retesting is built into Advanced: your first at the end of your first cycle, then every second cycle. On Core, add a retest whenever you want to see your change.

The score is what we measure. How it feels is what members tell us, self-reported alongside each retest, not a lab result.

Sleep quality

Sleep

▲ 2.0
6.0 8.0 /10

Self-reported · ~4 mo

Fatigue

Energy

▼ 3.0
6.0 3.0 /10

Lower is better · ~4 mo

Bloating

Digestion

▼ 5.0
8.0 3.0 /10

Lower is better · ~4 mo

Stress

Stress

▼ 2.0
7.0 5.0 /10

Lower is better · ~4 mo

An example retest, ~4 months in. Individual responses vary; your own retest measures your markers, before and after.

Readout → protocol

Your reading becomes a protocol.

Not a cupboard of bottles you're guessing at. A small, considered protocol built from what your gut actually showed, presorted and travel-ready, so the only thing you have to do is take it.

  • Activate, morning protocol Morning

    Activate

    With your first meal

    The morning foundation, built from what your reading found you're short on, to start the day steady.

  • Restore, evening protocol Evening

    Restore

    Before bed

    A calmer, overnight layer, added only when your reading calls for it. Nothing here by default.

  • Nourish, precision prebiotic powder Anytime

    Nourish

    Once a day

    The living layer. Precision prebiotics, fibre matched to your gut's fermentation machinery, plus a probiotic, to feed the microbes your reading showed were missing.

Sixteen weeks.
Measured, not promised.

A protocol built from your own reading, with a timeline you can hold us to, and a second reading to prove it moved.

The nb1 team at work

Real science, minus the white coats

Serious about your gut. Not clinical about you.

Your reading is built by real scientists and checked by an independent board before anything reaches you. No hype, no guesswork, just people who know guts doing the work behind the scenes, so you don't have to.

Every ingredient we use has to earn its place with real evidence. If it doesn't hold up, it doesn't go in your formula. Simple as that.

  • Built by scientists Designed by our own researchers, not marketers.
  • Checked independently An outside board signs off before it reaches you.
  • Evidence, not hype Every ingredient earns its place, or it's left out.

The board behind your reading

Real scientists design and check every formula, including two independent academics with no stake in the company. Meet the full board →

  • Dr. Polina Novikova
    Dr. Polina Novikova Chief Scientific Officer

    “When a formula is built from your actual gut, you’re not hoping something works, you’re giving it exactly what the biology asked for. That’s what makes the difference show up.”

  • Dr. Monica S. Matchado
    Dr. Monica S. Matchado Bioinformatics

    “The data tells us precisely which inputs will move your gut and which won’t. That’s the difference between a formula that does something and one that just looks good on a label.”

  • Dr. Marijn Lewis
    Dr. Marijn Lewis Immunology & gut health

    “Give a gut what it’s genuinely missing and it settles, becomes more resilient. That’s the outcome we build toward, not just a shorter ingredient list.”

  • Katia B. Otterstedt
    Katia B. Otterstedt Clinical research

    “Two people can need opposite formulas to reach the same result. Reading each gut is how we get both of them there, and how we can measure it actually worked.”

  • Prof. Dr. Dirk Haller
    Prof. Dr. Dirk Haller Independent validator · TU Munich

    “Building from one person’s reading produces a formula that genuinely fits them. That’s a more honest, and more effective, place to start than the average.”

  • Prof. Dr. Koen Venema
    Prof. Dr. Koen Venema Independent validator · Wageningen

    “Match the inputs to a gut’s real ecosystem and you change what that ecosystem produces. That’s where the meaningful results come from.”

How it works

From sample to your first cycle. Here's how it starts.

When you're ready to start the clock, here's how it goes. You order your kit and pay your first month, and we post your kit as soon as the payment goes through.

What arrives The nb1 gut kit: box, collection tube, instructions and transport bag
  1. 1

    Order your kit

    Choose a plan and check out. You pay your first month today, and we post your kit as soon as the payment goes through.

  2. 2

    Read your gut at home

    A two-minute sample, sealed and posted back in the same box. Send it back within 30 days, or your plan ends and your first month isn't refunded.

  3. 3

    Your formula begins

    We read your sample and build your protocol. Your plan starts from there, posted monthly and recalibrated every cycle as your gut changes.

Not sure yet? Compare Core and Advanced side by side first, no card needed.

See the plans

What it costs to read your gut

Two ways to read your gut.

Both start the same way: read your gut, build your formula, recalibrate every cycle. The difference is how deep the reading goes.

Core

We read your gut, and build your formula from it.

£94 /mo

or £99/mo month-to-month · 4-month minimum

  • Your gut, read at species level
  • A formula built from your data
  • Three parts, posted monthly, presorted
  • Recalibrates each cycle
Start with Core

4-month minimum, biology takes that long to shift. 1 month free, applied on your second month, on 4 and 12-month plans only; the month-to-month option is £99/mo. Compare in detail →

Start the clock

See what sixteen weeks can do. Your second month's on us.

Sign up and your second month's on us. We'll show you what to expect, when, and how we prove it moved. There's a four-month minimum, because biology takes that long to shift.

Your second month's on us on a 4 or 12-month plan. We'll email you how to claim it.

4 and 12-month plans only. The code cannot be used on the 1-month rolling plan.

You're in. Use code NB1FIRST at checkout on a 4 or 12-month plan to claim your second month, on us.
Meanwhile, see the full timeline

Ready to start the clock? See the plans →