Your first cycle, week by week

Give it sixteen weeks. Here's what changes.

Every supplement you've tried promised results "soon" and never said when. This one comes with a timeline built from your own gut reading, mapped across your first full cycle, and a reading at the end to show what actually moved. Here's what the weeks really look like.

Dr. Polina Novikova Prof. Dr. Dirk Haller NB1 science board

Built from your reading, measured against it every cycle. A timeline, not a promise.

★★★★★ Loved by early-access members through their first full cycle
The first cycle at a glance
Day 0
Read your gut at home
Weeks 1–4
Your formula begins
Weeks 9–12
The change most members notice
Week 16
We read you again & recalibrate
Build my formula Compare Core & Advanced →

Nothing's charged until your formula is made.

Why nothing's worked yet

It wasn't you. You were never given a timeline.

Every supplement you've tried worked the same way: take it, hope, wait for a payoff nobody ever defined, and quit when nothing obvious happened. With no timeline and nothing to measure, you were set up to give up.

1

Start another supplement

A probiotic, a fibre, whatever the reviews rated. No real idea what it's doing, or when it's meant to work.

2

Wait, and wonder

A week? A month? Nobody said. So you watch for a change with nothing to measure it against.

3

Feel nothing you can point to

Maybe a little better, maybe not. With no marker, you can't tell a real shift from a good day.

4

Quietly give up

You stop before anything could have landed. Back to square one, still guessing.

A protocol should tell you when. And prove it when the time comes.

What to expect and when

Sixteen weeks, because biology takes sixteen weeks to shift.

Not a contractual lock. The minimum window in which real biological change can be measured, tracked month by month.

Month 1

Settling in

Probiotic strains begin colonising. You may notice small shifts in digestion, normal as your gut adjusts.

Month 2

Early momentum

SCFA production rebuilds as fibre supply stabilises. Energy and sleep often respond first.

Month 3

Deepening balance

Team composition shifts measurably. Skin and immune markers tend to follow.

Month 4

The retest Advanced

On Advanced, the same pipeline runs again, now with your first blood biomarker panel layered in alongside it. Your formula recalibrates against everything that shifted, in your gut and your blood. On Core, add a retest whenever you want to see your change.

What members report
Sleep, self-reported▲ 2.0
Bloating, self-reported▼ 5.0
Fatigue, self-reported▼ 3.0
Stress, self-reported▼ 2.0

We don't promise change. We show it to you.

Retest your gut and see exactly what moved. The same markers, re-measured before and after. One number, objectively re-scored.

80.2/100
Overall microbiome score
▲ 11.9 pts up from 68.3
Retesting is built into Advanced: your first at the end of your first cycle, then every second cycle. On Core, add a retest whenever you want to see your change.

The score is what we measure. How it feels is what members tell us, self-reported alongside each retest, not a lab result.

An example retest, ~4 months in. Individual responses vary; your own retest measures your markers, before and after.

Readout → protocol

Your reading becomes a protocol.

Not a cupboard of bottles you're guessing at. A small, considered protocol built from what your gut actually showed, presorted and travel-ready, so the only thing you have to do is take it.

Activate, morning protocol Morning
Activate
With your first meal

The morning foundation, built from what your reading found you're short on, to start the day steady.

Restore, evening protocol Evening
Restore
Before bed

A calmer, overnight layer, added only when your reading calls for it. Nothing here by default.

Nourish, precision prebiotic powder Anytime
Nourish
Once a day

The living layer. Precision prebiotics, fibre matched to your gut's fermentation machinery, plus a probiotic, to feed the microbes your reading showed were missing.

Sixteen weeks.
Measured, not promised.

A protocol built from your own reading, with a timeline you can hold us to, and a second reading to prove it moved.

The NB1 team at work
Real science, minus the white coats

Serious about your gut. Not clinical about you.

Your reading is built by real scientists and checked by an independent board before anything reaches you. No hype, no guesswork, just people who know guts doing the work behind the scenes, so you don't have to.

Every ingredient we use has to earn its place with real evidence. If it doesn't hold up, it doesn't go in your formula. Simple as that.

Meet the people behind it
Built by scientists
Designed by our own researchers, not marketers.
Checked independently
An outside board signs off before it reaches you.
Evidence, not hype
Every ingredient earns its place, or it's left out.
The board behind your reading

Real scientists design and check every formula, including two independent academics with no stake in the company. Meet the full board

Dr. Polina Novikova
Dr. Polina Novikova
Chief Scientific Officer

“When a formula is built from your actual gut, you’re not hoping something works, you’re giving it exactly what the biology asked for. That’s what makes the difference show up.”

Dr. Monica S. Matchado
Dr. Monica S. Matchado
Bioinformatics

“The data tells us precisely which inputs will move your gut and which won’t. That’s the difference between a formula that does something and one that just looks good on a label.”

Dr. Marijn Lewis
Dr. Marijn Lewis
Immunology & gut health

“Give a gut what it’s genuinely missing and it settles, becomes more resilient. That’s the outcome we build toward, not just a shorter ingredient list.”

Katia B. Otterstedt
Katia B. Otterstedt
Clinical research

“Two people can need opposite formulas to reach the same result. Reading each gut is how we get both of them there, and how we can measure it actually worked.”

Prof. Dr. Dirk Haller
Prof. Dr. Dirk Haller
Independent validator · TU Munich

“Building from one person’s reading produces a formula that genuinely fits them. That’s a more honest, and more effective, place to start than the average.”

Prof. Dr. Koen Venema
Prof. Dr. Koen Venema
Independent validator · Wageningen

“Match the inputs to a gut’s real ecosystem and you change what that ecosystem produces. That’s where the meaningful results come from.”

Swipe to meet the board
How it works

From sample to your first cycle. Here's how it starts.

When you're ready to start the clock, here's how it goes. Nothing's charged today, you leave your details and we post your kit first.

What arrives The NB1 gut kit: box, collection tube, instructions and transport bag
  1. 1

    Order your kit

    Choose a plan and check out. No charge today, we simply validate your card and post your kit.

  2. 2

    Read your gut at home

    A two-minute sample, sealed and posted back in the same box. Send it back within 30 days, a one-time £49 fee only applies if you don't.

  3. 3

    Your formula begins

    We read your sample and build your protocol. Your plan starts from there, posted monthly and recalibrated every cycle as your gut changes.

Not sure yet? Compare Core and Advanced side by side first, no card needed.

See the plans
What it costs to read your gut

Two ways to read your gut.

Both start the same way: read your gut, build your formula, recalibrate every cycle. The difference is how deep the reading goes.

Core

We read your gut, and build your formula from it.

£99 /mo
or £109/mo month-to-month · 4-month minimum
  • Your gut, read at species level
  • A formula built from your data
  • Three parts, posted monthly, presorted
  • Recalibrates each cycle
Start with Core
Most informed
Advanced

Gut and blood. Your formula rebuilds every cycle.

£149 /mo
everything in Core, plus blood biomarkers
  • Blood biomarkers, alternating with gut
  • Formula rebuilds from every analysis
  • 125+ ingredient library, on request
  • Priority support from the team
Start with Advanced
Start the clock

See what sixteen weeks can do.

We read your gut and build your formula from it, then show you what to expect, when, and how we prove it moved. There's a four-month minimum, because biology takes that long to shift.

Order your kit

Nothing's charged until your formula is made. Compare Core & Advanced →

Built from your gut readingNothing charged until it's made.
Order your kit